Leukaemia treatment research. Fluorescence light micrograph of tissue from a Drosophila fruit fly larva, being used to investigate gene-based treatments for a type of leukaemia (blood cell cancer). The fusion protein CBFA2T3-GLIS2 is a key driver of paediatric acute megakaryoblastic leukemia (AMKL). Here, researchers have expressed this protein (red) in larval Drosophila (fruit fly) wing disc cells, confirming a major role for the BMP (bone morphogenetic protein) signalling pathway. This pathway may provide a target for new therapies. The tissue types and colours highlighted here are cell nuclei (green) and actin filaments (pink).